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Foundations 2 - Fluids & Electrolyte - Flashcards

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Class:NURS 231 - Found In Nurs II
Subject:Nursing
University:The University of Tennessee-Martin
Term:Spring 2011
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2 Major Fluid Compartments Water makes up 55-60% of total body weight Intracellular fluid - 2/3 total body h20 (25 Liters) Extracellular fluid - 1/3 total body h20 (15 Liters) -Composed of 20% plasma and 80% interstitial fluid
Filtration Filtration is commonly the mechanical or physical operation which is used for the separation of solids from fluids (liquids or gases) by interposing a medium through which only the fluid can pass.
Hydrostatic Pressure The force of the weight of water molecules pressing against the confining walls of a space. Water-Pushing pressure
Diffusion The free movement of solute (particles) across a permeable membrane down a concentration gradient.
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Osmosis The movement of solvent (water) through a selectively permeable membrane. From area of more dilute into area of more concentration
Osmolarity Osmolarity is the measure of solute (particle) concentration, defined as the number of osmoles (Osm) of solute per liter (L) of solution (osmol/L or Osm/L).
Milliosmole The total number of solute particles contained in a solution
Active Transport Active transport is the movement of a substance against its concentration gradient (from low to high concentration). Requires energy Uses Na+/K+ pumps. -More Na+ in ECF -More K+ in ICF
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Aldosterone Aldosterone is a hormone that increases the reabsorption of sodium ions and water. Secreted by the adrenal cortex Release stimulated by decreased Na+ in ECF or increased Na+ in urine. Preserves Na+ loss
Antidiuretic Hormone AKA: Vasopressin Acts on kidney tubules making them more permeable to water, which increases water reabsorption and causes dilution of the blood. Produced in the brain and stored in the posterior pituitary gland Release controlled by the hypothalamus in response to change in blood osmolarity
Natriuretic Peptide Natriuretic peptide refers to a peptide which induces natriuresis (the discharge of sodium through urine). Secreted by cells in the lining of the atria and ventricles Secreted in response to increased blood volume and increased BP Causes increase urine output and increased glomerular filtration rate.
Hypervolemia Hypervolemia, or fluid overload, is the medical condition where there is too much fluid in the blood (ECF). Rarely happens in people with normal kidney and heart function. Monitor patients with CHF, chronic renal failure, and chronic liver disease.
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Symptoms of Hypervolemia Weight gain Distended neck veins (JVD) Polyuria Hypertension Full, bounding pulses Crackles in lungs (pulmonary edema, SOB) Elevated RR Ascites Peripheral edema Decreased Hct, BUN (dilution)
Ions Cations (+) Anions (-) Body fluids maintain neutral balance Most enter the body via ingested food.
Sodium (Na+) Normal lab value: 136-145 mEq/L Most abundant cation (+) in ECF Controls ECF volume and water distribution Regulated by the kidney hormones Angiontensin II and Aldosterone Na+ content of the body may change, but concentration will remain constant due to corresponding water volume changes. Average dietary intake: 6-14g/day
What does Sodium (Na+) do? Na+ is vital for: Skeletal muscle contraction Cardiac contraction Nerve impulse transmission Normal ECF osmolarity Normal ECF volume
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Potassium (K+) Normal lab value: 3.5-5.0 mEq/L Most abundant cation (+) in ICF Regulated by changing amount secreted in the kidney tubules Average dietary intake: 2-20 g/day
What does Potassium do? (K+) Functions of K+: Regulation of protein synthesis Regulation of glucose use and storage Maintenance of action potentials
Calcium (Ca++) Normal lab value: 9.0-10.5 mg/dL or 2.25-2.75 mmol/L Regulated by Parathyroid and Thyrocalcitonin Enters via dietary intake Requires Vitamin D Excess stored in bones Average daily intake: 800-1200mg
What does Calcium (C++) do? Functions of Ca++: Bone strength and density Activation of enzymes or reactions Skeletal muscle contraction Cardiac muscle contraction Nerve impulse transmission Blood clotting
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Phosphorus (P) Normal lab value: 3.0-4.5 mg/dL or 0.97-1.45 mmol/L Major anion (-) of ICF 80% is found in bones Average daily intake: 1-2g Plasma levels exist in balance with Ca++ levels
What does Phosphorus (P) do? Functions of P: Activating B-complex vitamins Forming and activating adenosine triphosphate (ATP) Assisting in cell division Cooperating in nutrient metabolism. (Carbohydrates, Proteins, and Lipids)
Magnesium (Mg++) Normal lab value: 1.3-2.1 mg/dL or 0.65-1.05 mmol/L Forms a cation (+) when dissolved in H20 Mostly found in the ICF Excreted by the kidneys and absorbed in the GI tract Average daily intake: 300mg
What does Magnesium (M++) do? Functions of Mg++: Skeletal muscle contraction Carbohydrate metabolism ATP formation B-complex vitamin activation DNA synthesis Protein synthesis Regulate blood coagulation
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Hyponatremia Low sodium (<136 mEq/L) Most common electrolyte disorder Common causes: Diuretics, vomiting, sweating, bleeding, Renal failure, Movement out of ECF, Failure of Na/K pump, Diabetic ketoacidosis, Hypoxia, Liver failure (third spacing), Fresh water drowning, and over administration of hypotonic solutions
S/S of Hyponatremia Confusion Headache N&V Generalized muscle weakness progressing to coma (late stage) Fatigue Postural hypotension Anorexia Abdominal cramps Weight loss
Treatment of hyponatremia Monitor I&O, Wt, VS, LOC Monitor serum sodium, serum osmolarity Restrict hypotonic fluids Encourage foods or fluids high in Na+ Careful use of hypertonic IV fluids
Hypernatremia High sodium (>145 mEq/L) Common causes: Renal failure (inability to excrete Na+), Hypertonic IV fluids and/or tube feedings, Excessive salt ingestion, and decreased fluid intake
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S/S of Hypernatremia Thirst Dry, sticky mucous membranes Low UOP Muscle twitching Hypertension Firm, rubbery tissue turgor Manic excitement (severe) Tachycardia (severe) Death (severe)
Treatment of Hypernatremia Monitor: I&O, Wt, VS, LOC Monitor serum sodium levels and serum osmolarity Careful use of hypotonic or isotonic IV fluids Restrict foods, fluids, meds high in Na+ Seizure precaution
Hypocalcemia Low calcium (<9.0 mg/dL or < 2.25 mmol/L) Usually due to a failure of normal regulatory mechanisms, such as acute or chronic renal failure, but can also occur with malabsorption syndromes, acute pancreatitis, and alkalosis Low levels increase excitability of nerves and muscles (especially GI) If serum levels are low, bones release calcium and become osteoporotic
S/S of Hypocalcemia Muscle spasms, cramps, tremors Hyperactive reflexes Diarrhea Tingling of fingers, toes, lips, face Tetany Positive Trousseau’s sign-carpopedal spasm (hand spasms when BP cuff inflated 3-4 minutes) Seizures Arrhythmias EKG changes
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Treatment of Hypocalcemia Monitor labs Cardiac monitoring Seizure precaution Decrease stimuli Oral Ca++ supplements and/or Vit D (give supplements between meals for better absorption) IV Ca++ Teach pt about foods high in Ca++
Hypercalcemia High calcium (>10.5 mg/dL or >2.75 mmol/L) Common causes:Excessive intake, Malignancy, Hyperparathyroidism, Decreased renal secretion, and diuretic use
S/S of Hypercalcemia Decreased excitability of nerves Muscle weakness N/V, constipation Hypoactive bowel sounds Extreme thirst Polyuria (if normal kidney function) Kidney stones Blood clots Arrhythmias EKG changes
Treatment of Hypercalcemia Monitor high risk pts: long term bedrest, CA, hyperparathyroidism Increase fluid intake to 3-4 liters per day Assess Homan’s sign Cardiac monitoring Safety (muscle weakness) Assess bowel sounds Early and frequent ambulation Teach pt. to avoid foods high in Ca++ or not to overuse supplements
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Hypomagnesemia Low MG++ (<1.3 mg/dL or <0.65 mmol/L) Common causes: Frequently co-exists with hypokalemia, Vomiting, Diarrhea, suctioning, Prolonged malnutrition, renal disorders, burns, diabetic ketoacidosis, and hypercalcemia
S/S of Hypomagnesemia Tachycardia Arrhythmias Hypotension Muscle spasms Tetany Hyperactive reflexes Positive Trousseau’s LOC changes-confusion, agitation Seizures
Treatment of Hypomagnesemia Cardiac monitoring Seizure precautions Oral, IM, or IV Mg salts Monitor labs VS LOC DTRs Safety- LOC changes Teach patient to increase foods high in Mg++
Hypermagnesemia High Mg++ (>2.1 mg/dL or >1.05 mmol/L) Rare Common causes: Increased intake and decreased excretion Antacids Laxatives IV adm of Mg++ Renal insufficiency
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S/S of Hypermagnesemia Lethargy and drowsiness Depressed respirations Low B/P Bradycardia progressing to cardiac arrest Hypoactive reflexes Coma Decreased UOP
Treatment of Hypermagnesemia VS frequently (can decrease rapidly) Labs Monitor reflexes, lung sounds, DTRs Cardiac monitoring I&O Safety: drowsiness, hypotension, bradycardia Teach pt to avoid foods/meds high in Mg++
Hypokalemia Low K+ (<3.5 mEq/L) Common causes: Excessive vomiting, suctioning, diarrhea Diuretics, laxatives, insulin Alkalosis Hemodilution from overhydration, renal disease Acute alcoholism
S/S of Hypokalemia Muscle weakness and atony N/V Constipation Hypotension, elevated pulse (due to decreased cardiac output) Alkalosis
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Treatment of Hypokalemia Cardiac monitoring Safety (hypotension & muscle weakness) UOP Oral K+ supplements (with food) NEVER give K+ IV push Teach pt to increase potassium intake Treat underlying cause
Hyperkalemia High K+ (>5.0 mEq/L) Common causes: Use of salt substitute or K+ supplements Malfunctioning Na/K pump Cell distruction, crushing injuries, burns, hemolysis Surgery Inadequate potassium excretion Sepsis Fever
S/S of Hyperkalemia Muscle weakness, paralysis N/V/D Alterations in cardiac muscle stimulation and relaxation Dysrhythmias, bradycardia, cardiac arrest LOC changes Numbness in hands and feet
Treatment of Hyperkalemia Cardiac monitoring VS Safety – bradycardia, muscle weakness, LOC Kayexalate enema or oral Calcium gluconate Glucose and insulin mixture (moves K+ into cells) Teach client to avoid foods high in K+: cantaloupe, bananas, apricots, broccoli, salt substitutes
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 2 Major Fluid CompartmentsWater makes up 55-60% of total body weight

Intracellular fluid - 2/3 total body h20 (25 Liters)

Extracellular fluid - 1/3 total body h20 (15 Liters)
-Composed of 20% plasma and 80% interstitial fluid
 FiltrationFiltration is commonly the mechanical or physical operation which is used for the separation of solids from fluids (liquids or gases) by interposing a medium through which only the fluid can pass.
 Hydrostatic PressureThe force of the weight of water molecules pressing against the confining walls of a space.

Water-Pushing pressure
 DiffusionThe free movement of solute (particles) across a permeable membrane down a concentration gradient.
 OsmosisThe movement of solvent (water) through a selectively permeable membrane.

From area of more dilute into area of more concentration
 OsmolarityOsmolarity is the measure of solute (particle) concentration, defined as the number of osmoles (Osm) of solute per liter (L) of solution (osmol/L or Osm/L).
 MilliosmoleThe total number of solute particles contained in a solution
 Active TransportActive transport is the movement of a substance against its concentration gradient (from low to high concentration).

Requires energy

Uses Na+/K+ pumps.
-More Na+ in ECF
-More K+ in ICF
 AldosteroneAldosterone is a hormone that increases the reabsorption of sodium ions and water.

Secreted by the adrenal cortex

Release stimulated by decreased Na+ in ECF or increased Na+ in urine.

Preserves Na+ loss
 Antidiuretic HormoneAKA: Vasopressin

Acts on kidney tubules making them more permeable to water, which increases water reabsorption and causes dilution of the blood.

Produced in the brain and stored in the posterior pituitary gland

Release controlled by the hypothalamus in response to change in blood osmolarity
 Natriuretic PeptideNatriuretic peptide refers to a peptide which induces natriuresis (the discharge of sodium through urine).

Secreted by cells in the lining of the atria and ventricles

Secreted in response to increased blood volume and increased BP

Causes increase urine output and increased glomerular filtration rate.
 HypervolemiaHypervolemia, or fluid overload, is the medical condition where there is too much fluid in the blood (ECF).

Rarely happens in people with normal kidney and heart function.

Monitor patients with CHF, chronic renal failure, and chronic liver disease.
 Symptoms of HypervolemiaWeight gain
Distended neck veins (JVD)
Polyuria
Hypertension
Full, bounding pulses
Crackles in lungs (pulmonary edema, SOB)
Elevated RR
Ascites
Peripheral edema
Decreased Hct, BUN (dilution)
 IonsCations (+)

Anions (-)

Body fluids maintain neutral balance

Most enter the body via ingested food.
 Sodium (Na+)Normal lab value: 136-145 mEq/L

Most abundant cation (+) in ECF

Controls ECF volume and water distribution

Regulated by the kidney hormones Angiontensin II and Aldosterone

Na+ content of the body may change, but concentration will remain constant due to corresponding water volume changes.

Average dietary intake: 6-14g/day
 What does Sodium (Na+) do? Na+ is vital for:
Skeletal muscle contraction

Cardiac contraction

Nerve impulse transmission

Normal ECF osmolarity

Normal ECF volume
 Potassium (K+)Normal lab value: 3.5-5.0 mEq/L

Most abundant cation (+) in ICF

Regulated by changing amount secreted in the kidney tubules

Average dietary intake: 2-20 g/day
 What does Potassium do? (K+)Functions of K+:
Regulation of protein synthesis

Regulation of glucose use and storage

Maintenance of action potentials
 Calcium (Ca++)Normal lab value: 9.0-10.5 mg/dL or 2.25-2.75 mmol/L

Regulated by Parathyroid and Thyrocalcitonin

Enters via dietary intake

Requires Vitamin D

Excess stored in bones

Average daily intake: 800-1200mg
 What does Calcium (C++) do?Functions of Ca++:
Bone strength and density

Activation of enzymes or reactions

Skeletal muscle contraction

Cardiac muscle contraction

Nerve impulse transmission

Blood clotting
 Phosphorus (P)Normal lab value: 3.0-4.5 mg/dL or 0.97-1.45 mmol/L

Major anion (-) of ICF

80% is found in bones

Average daily intake: 1-2g

Plasma levels exist in balance with Ca++ levels
 What does Phosphorus (P) do?Functions of P:
Activating B-complex vitamins

Forming and activating adenosine triphosphate (ATP)

Assisting in cell division

Cooperating in nutrient metabolism. (Carbohydrates, Proteins, and Lipids)
 Magnesium (Mg++)Normal lab value: 1.3-2.1 mg/dL or 0.65-1.05 mmol/L

Forms a cation (+) when dissolved in H20

Mostly found in the ICF

Excreted by the kidneys and absorbed in the GI tract

Average daily intake: 300mg
 What does Magnesium (M++) do?Functions of Mg++:
Skeletal muscle contraction

Carbohydrate metabolism

ATP formation

B-complex vitamin activation

DNA synthesis

Protein synthesis

Regulate blood coagulation
 HyponatremiaLow sodium (<136 mEq/L)

Most common electrolyte disorder

Common causes: Diuretics, vomiting, sweating, bleeding, Renal failure, Movement out of ECF, Failure of Na/K pump, Diabetic ketoacidosis, Hypoxia, Liver failure (third spacing), Fresh water drowning, and over administration of hypotonic solutions
 S/S of HyponatremiaConfusion
Headache
N&V
Generalized muscle weakness progressing to coma (late stage)
Fatigue
Postural hypotension
Anorexia
Abdominal cramps
Weight loss
 Treatment of hyponatremiaMonitor I&O, Wt, VS, LOC

Monitor serum sodium, serum osmolarity

Restrict hypotonic fluids

Encourage foods or fluids high in Na+

Careful use of hypertonic IV fluids
 HypernatremiaHigh sodium (>145 mEq/L)

Common causes: Renal failure (inability to excrete Na+), Hypertonic IV fluids and/or tube feedings, Excessive salt ingestion, and decreased fluid intake
 S/S of HypernatremiaThirst
Dry, sticky mucous membranes
Low UOP
Muscle twitching
Hypertension
Firm, rubbery tissue turgor
Manic excitement (severe)
Tachycardia (severe)
Death (severe)
 Treatment of HypernatremiaMonitor: I&O, Wt, VS, LOC
Monitor serum sodium levels and serum osmolarity
Careful use of hypotonic or isotonic IV fluids
Restrict foods, fluids, meds high in Na+
Seizure precaution
 HypocalcemiaLow calcium (<9.0 mg/dL or < 2.25 mmol/L)

Usually due to a failure of normal regulatory mechanisms, such as acute or chronic renal failure, but can also occur with malabsorption syndromes, acute pancreatitis, and alkalosis

Low levels increase excitability of nerves and muscles (especially GI)

If serum levels are low, bones release calcium and become osteoporotic
 S/S of HypocalcemiaMuscle spasms, cramps, tremors
Hyperactive reflexes
Diarrhea
Tingling of fingers, toes, lips, face
Tetany
Positive Trousseau’s sign-carpopedal spasm (hand spasms when BP cuff inflated 3-4 minutes)
Seizures
Arrhythmias
EKG changes
 Treatment of HypocalcemiaMonitor labs
Cardiac monitoring
Seizure precaution
Decrease stimuli
Oral Ca++ supplements and/or Vit D (give supplements between meals for better absorption)
IV Ca++
Teach pt about foods high in Ca++
 HypercalcemiaHigh calcium (>10.5 mg/dL or >2.75 mmol/L)

Common causes:Excessive intake, Malignancy, Hyperparathyroidism, Decreased renal secretion, and diuretic use
 S/S of HypercalcemiaDecreased excitability of nerves
Muscle weakness
N/V, constipation
Hypoactive bowel sounds
Extreme thirst
Polyuria (if normal kidney function)
Kidney stones
Blood clots
Arrhythmias
EKG changes
 Treatment of HypercalcemiaMonitor high risk pts: long term bedrest, CA, hyperparathyroidism
Increase fluid intake to 3-4 liters per day
Assess Homan’s sign
Cardiac monitoring
Safety (muscle weakness)
Assess bowel sounds
Early and frequent ambulation
Teach pt. to avoid foods high in Ca++ or not to overuse supplements
 HypomagnesemiaLow MG++ (<1.3 mg/dL or <0.65 mmol/L)

Common causes: Frequently co-exists with hypokalemia, Vomiting, Diarrhea, suctioning, Prolonged malnutrition, renal disorders, burns, diabetic ketoacidosis, and hypercalcemia
 S/S of HypomagnesemiaTachycardia
Arrhythmias
Hypotension
Muscle spasms
Tetany
Hyperactive reflexes
Positive Trousseau’s
LOC changes-confusion, agitation
Seizures
 Treatment of HypomagnesemiaCardiac monitoring
Seizure precautions
Oral, IM, or IV Mg salts
Monitor labs
VS
LOC
DTRs
Safety- LOC changes
Teach patient to increase foods high in Mg++
 HypermagnesemiaHigh Mg++ (>2.1 mg/dL or >1.05 mmol/L)

Rare

Common causes:
Increased intake and decreased excretion
Antacids
Laxatives
IV adm of Mg++
Renal insufficiency
 S/S of HypermagnesemiaLethargy and drowsiness
Depressed respirations
Low B/P
Bradycardia progressing to cardiac arrest
Hypoactive reflexes
Coma
Decreased UOP
 Treatment of HypermagnesemiaVS frequently (can decrease rapidly)
Labs
Monitor reflexes, lung sounds, DTRs
Cardiac monitoring
I&O
Safety: drowsiness, hypotension, bradycardia
Teach pt to avoid foods/meds high in Mg++
 HypokalemiaLow K+ (<3.5 mEq/L)

Common causes:
Excessive vomiting, suctioning, diarrhea
Diuretics, laxatives, insulin
Alkalosis
Hemodilution from overhydration, renal disease
Acute alcoholism
 S/S of HypokalemiaMuscle weakness and atony
N/V
Constipation
Hypotension, elevated pulse (due to decreased cardiac output)
Alkalosis
 Treatment of HypokalemiaCardiac monitoring
Safety (hypotension & muscle weakness)
UOP
Oral K+ supplements (with food)
NEVER give K+ IV push
Teach pt to increase potassium intake
Treat underlying cause
 HyperkalemiaHigh K+ (>5.0 mEq/L)

Common causes:
Use of salt substitute or K+ supplements
Malfunctioning Na/K pump
Cell distruction, crushing injuries, burns, hemolysis
Surgery
Inadequate potassium excretion
Sepsis
Fever
 S/S of HyperkalemiaMuscle weakness, paralysis
N/V/D
Alterations in cardiac muscle stimulation and relaxation
Dysrhythmias, bradycardia, cardiac arrest
LOC changes
Numbness in hands and feet
 Treatment of HyperkalemiaCardiac monitoring
VS
Safety – bradycardia, muscle weakness, LOC
Kayexalate enema or oral
Calcium gluconate
Glucose and insulin mixture (moves K+ into cells)
Teach client to avoid foods high in K+: cantaloupe, bananas, apricots, broccoli, salt substitutes