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Karma
| Class: | ZOO 250 - ANATOMY AND PHYSIOLOGY LECTURE I |
| Subject: | Zoology |
| University: | Southeastern Louisiana University |
| Term: | Spring 2011 |
INCORRECT
CORRECT

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Anatomy
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Study of form |
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examining the structure of the human body
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Physiology
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study of function |
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Hippocrates
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Aristotle
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Galen
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Avicenna Meimonides
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Versallus
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Hooke
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Leeuwenhook
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Schwann/Schledin
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Charles Darwin
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evolutions
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theory of natural selection
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Vestigal Organs
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Arboreal adaptations
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Bipedalism
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Atom-molecule-macromolecule-organelle-cell-tissue-organ-organsystem-organism
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Hierarchy of complexity |
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chemical elements (95% of body weight)
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oxygen, carbon, hydrogen, nitrogen, calcium & phosphorous |
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Minerals (4% body weight)
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Calcium, Phosphorous, Chlorine, Mg, K, Na, I Fe, Zn, Cu & S |
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Electrolytes
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needed for nerve & muscles functions are mineral salts |
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Radioactity
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Isotopes |
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Isotopes
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molecules
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2 or more atoms united by a chemical bond |
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Chemical Reaction
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Decomposition Reactions
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synthesis
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Small to big a + b > ab |
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Metabolism
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All the chemical reactions of the body
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Catabolism
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Energy releasing (exergonic) decomposition reactions |
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Anabolism
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Energy storing (endergonic) synthesis reactions
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Organic Macromolecules
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Carbohydrates lipids protein nucleic acid |
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Squamous Cells
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thin, flat , and often have a bulge where the nucleus is much like the shape of a fried egg |
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Polygonal cells
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irregularly angular shaped with four, five, or more sides |
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Stellate cell
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nerve cells that have multiple extensions that give them a starlike shape |
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Cuboidal Cells
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squarish and approximately as tall as they are wide |
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Columnar Cells
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line the intestines and are markedly taller than wide liver cells are good example |
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Spheroid
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egg cells and fat cells round to ovale |
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Fibrous
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Skeletal muscle cells
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10 - 15 micrometers in diameter
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human cell size |
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100 micrometer in diameter
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egg cells |
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1 meter long
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nerve cells |
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Major constituents of cell
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Plasma Membrane
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made of proteins and lipids |
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Cytosol
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intercellular fluid |
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Diffusion
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temp, molecular weight, steepness of gradient, membrane surface area, membrane permeability
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factors that affect the diffusion rate |
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Temperature
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increase temp increase the motion |
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molecular weight
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larger molecules move slower |
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steepness of gradient
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increase the difference and increase the rate |
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membrane surface area
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increase the area increase the rate |
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membrane permeability
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increase the permeability and increase the rate |
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osmosis
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flow of water from side w/ higher water concentration to the side with lower water concentration across a selectively permeable membrane |
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hypotonic environment
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environment has less concentration of solute cell swells and may burst (lyse) |
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hypertonic environment
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environment has more concentration of solute cell may shrink and shrivel (crenate) |
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Isotonic solution
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everything equals inside and outside environments no change in shape nor size |
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Active transport
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carrier-mediated trasport of solute through a membrane up (against) its concentration gradient ATP energy is consumed examples: sodium potassium pump keeps K+ concentration higher inside the cell |
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sodium potassium pump
(ICF, ECF)
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consumes one ATP and exchanges three Na+ for 2 K+ K+ is higher in Na+ is higher in |
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Vescular Transport
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processes that move particles through the membrane in vesicles |
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Endocytosis
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vesicular processes that bring material into the cell phagoyctosis pinocytosis receptor |
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Phagoctosis
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cell eating (white blood cells) |
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Pinocytosis
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cell drinking |
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Receptor
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mediated endocytosis----particle bind to specific receptor on plasma membrane |
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Exocytosis
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discharging material from the cell example: discharge of insulin |
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receptor mediated endocytosis
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Neutrophil Phagocytosis
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5 different types white blood cells |
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Integuma system
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protection skin, hair, naile |
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Skeletal System
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structure, support |
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muscular system
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movement |
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lymphatic system
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lymph nodes, tonsils, speed, thymus lympthatic organs are dominated by WBCs |
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Respiratory System
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Cellular respiration |
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urinary system
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removing wastes/ regulates blood pressure |
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nervous system
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sensory & internal communication |
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endocrine system
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hormones |
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circulatory system
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blood flow, distribution of nutrients heart and blood vessels blue blood until it reaches the lungs ; further from heart darker blood |
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Digestive system
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nutrients breakdown and absorption metabolism and disposal and cleansing of blood |
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reproductive system
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dont need this to live |
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anatomical position
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standard frame of reference for anatomical descriptions & dissections palms are supinated (face foward) |
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Sagittal Plane
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right and left regions median (midsagittal) plane |
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Frontal Plane
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anterior (front) and Posterior (back) portions |
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transverse Plane
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superior (upper) and inferior (lower) portions |
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ventral/ dorsal
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going toward front/back |
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superior/inferior
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above/below |
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proximal/distal
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close to pt attachment/ far |
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medial/lateral
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toward inside/ outside |
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superficial/deep
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close to surface/ far |
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homeostasis
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body's ability to detect change and activate mechanisms that oppose it. |
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negative feedback
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keeps variable close to the set point example thermoregulation |
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positive feedback
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leads to greater change in the same directions example: child birth |
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Epithelium Tissue
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simple epithelia
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all cells touch basement membrane can be: simple squamous simple cuboidal simple columnar pseudostratified |
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stratified epithelia
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not all cell touch basement membrane; multiple layers 2 to 20 or more layers of cells can be: stratified squamous stratified cuboidal stratified columnar transitional epithelium |
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simple squamous
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simple cuboidal
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simple columnar
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Psudostratified
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goblet cells
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mucus secreting cells |
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stratified squamous
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keratinized and non karatinized |
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keratinized
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nonkeratinized
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stratified cuboidal
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transitional epithelium
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change from round to flat when stretched example: ureter and bladder |
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connective tissue
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four types: fibrous, loose, dense, supportive |
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fibrous CT
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cells (fibroblast, macrophages, leukocytes, plasma cells, mast cells, adipocytes) fibers (collagenous, reticular, elastic) |
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Macrophages
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fibrous cells able to phagocytise |
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Leukocytes
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fibrous white blood cells immune protection |
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Plasma Cells
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fibrous CT cell that secretes antibodies |
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Mast Cell
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fibrous CT cell secret heparin and histamine |
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heparin
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blood doesnt clot |
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histamine
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widen blood vessels |
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adipocytes
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fibrous ct fat cells store lipids |
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collagenous fibers
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cant stretch |
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reticular fibers
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coated with glycoprotein |
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elastic fibers
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very stretchable |
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Loose CT
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Areolar tissue reticular tissue adipose tissue |
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areolar tissue
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all cell types present, mostly collagenus fibers underlies all epithelia, in serous membrane, between muscles, passageways for nerves and blood vessels |
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reticular tissue
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mesh of reticular fibers and fibroblasts found in lymph nodes, spleen, thymus, and bone marrow |
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adipose tissue
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energy storage, insulation, cushioning areolar tissue, reticular tissue, and blood capillaries between cells |
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Dense CT
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Dense regular and Dense irregular |
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Dense regular
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all fibers running parallel tendons and ligaments |
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tendons
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muscle to bone most important to stabilizing joing |
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ligaments
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bone to bone |
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dense irregular
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deeper layer of skin; capsules around organs |
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supportive CT
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cartilage
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hyaline cartilage
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elastic cartilage
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Fibrocartilage
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fluid CT
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blood |
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blood
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plasma forms : erythrocytes, leukocyte, and platelets |
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erythrocytes
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leukocytes
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Platelets
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muscular and nervous
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excitable tissues |
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nervous tissue
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neurosoma
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cell body |
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dendrites
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axon
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nerve fiber
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muscular tissue
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three types
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skeletal muscle
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cardiac muscle
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smooth muscles
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example: labor |
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endocrine Glands
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lose contact with surface
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exocrine glands
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maintain contact with body surface by way of a duct type:
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serous glands
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produce thin, watery secretions type of exocrine gland |
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mucous glands
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found on tongue and roof of mouth type of exocrine glands |
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mixed glands
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both serous and mucous glands |
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cytogenic glands
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release whole cells sperm and egg cells |
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methods of secretion
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merocrine glands apocrine glands holocrine glands |
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merocrine glands
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vesicles release secretion by exocytosis
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apocrine glands
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merocrine mode of secretion
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holocrine gland
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cells accumulate a product and the entire cell disintegrates
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epidermis
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karatinized stratified squamous 5 layers: stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, stratum basale
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stratum corneum
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stratum lucidum
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stratum granulosum
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3-5 layers thick keratohyalin granule
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stratum spinosum
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thickest in most skin produces keratin filaments 8-10 cells thick |
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stratum basale
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one cell layer thick stem cells divide keratinocytes melanocytes----melanin tactile (merkel) cells----touch receptor cells |
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dermis
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malignant melanoma
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basal cell carcinoma
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most common arises from cells in stratum basal |
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squamous cell carcinoma
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papillary layer
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reticular layer
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hypodermis
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cyanosis
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deficiency of oxygen in blood cold weather, airway abstruction |
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erythema
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dilated cutaneous vessels hot weather, exercise, anger |
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pallor
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little blood flow through the skin low blood pressure, anemic, circulatory shock |
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albinism
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genetic lack of melanin |
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jaundice
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excess of bilirubin in blood yellowing of skin, eye |
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hematoma
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mass of clotted blood bruise, hicky |
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flat
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curly hair shape |
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round
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straight hair shape |
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red hair
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more phamelanin than eumalanin |
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black hair
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high concentration of eumalanin |
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blonde hair
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very little eumalanin more phamelanin |
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grey
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absence of melanin cortex become hollowed out |
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debridement
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removal of eschar |
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1st degree burn
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havent gone through the skin |
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2nd degree burn
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gone throught the dermis |
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3rd degree burn
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need skin graphs burn through the dermis and epidermis down to bone |
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functions of the skin
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resistance to trauma and infection
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keratin acid mantle |
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other barrier functions
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waterproofing UV radiation harmful chemicals |
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Vitamin D synthesis
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skin first step liver and kidneys complete process |
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sensation
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skin is our most extensive sense organ |
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thermoregulation
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thermoreceptors vasoconstriction/ vasodilation |
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nonverbal communication
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acne, birthmark, or scar |
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Transdermal absorption
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administration of certain drugs steadily through this skin----adhesive patches |
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Long, short, flat, irregular
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Long bone
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rigid levers acted upon by muscle (femur and ulna) structure:
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periosteum
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outer layer of long bone |
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endosteum
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inner layer of long bone cells that can deposit or breakdown |
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nutrient foramina
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blood vessels are allowed to penetrate the bones |
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epiphyses
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large end of long bone |
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diaphysis
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shaft of long bone |
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epiphysial line
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seperates piphyses from diaphysis in adults |
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compact
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surface of all bones |
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spongy
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in the ends of long bones |
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marrow cavity
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in the middle and contains the marrow |
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short bones
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glide across one another in multiple directions carpals and tarsals |
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flat bones
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protect soft organs scapula, sternum, cranial, ribs |
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irregular bones
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skull bones vertebrate, sphenoid, ethnoid |
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bone marrow
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red----- myeloid tissue (child) yellow----(adults) |
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four principle types of bone cells
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osteogenic cell osteoblasts osteocytes osteoclast |
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osteogenic cell
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give rise to osteoblast stem cell |
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osteoblast
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buil start producing matrix to form bone becomes trapped in matrix and becomes osteocytes |
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osteocytes
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mature bone cell |
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osteoclast
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catastrophe same stem cell as blood develops from stem cells from a different origin surface of bone bone dissolving cells |
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compact bone
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spongy bone
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osteogenesis
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in the human fetus and infant, bone develops by two methods: intramembranous ossification endochondral ossification |
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interstitial growth
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part of bone growth bones increase in length |
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appositional growth
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the deposition of new bone at the surface |
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bone remodeling
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occurs throughout life 10% per year |
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Achondroplastic dwarfism
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failure of cartilage growth in metaphysis |
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pituitary dwarfism
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lack of growth hormone |
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calcium homeostasis
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is regulated by three hormones: calcitriol, calcitonin, and parathyroid hormone |
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hypocalcemia
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blood calcium deficiency Na enters cells to easily and excites muscle spasms, tenisis |
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hypercalcemia
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blood calcium excess Na channels less responsive, nerve and muscular tissue depress and slugish very rare |
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calcitriol
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calcitonin
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decreases blood calcium back to normal produced by the thyroid gland |
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parathyroid hormone secretion
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correction for hypocalcemia
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stress fracture
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abnormal trauma to a bone |
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pathological fracture
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weakend by disease |
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nondisplaced
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cracked but bones still aligned |
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displaced
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bones are not aligned completely broken |
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comminuted
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bones broken in 3 or more places |
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greenstick
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incomplete fractured causing stress on another bone |
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closed treatment
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no surgery |
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opened treatment
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plates screws to fix |
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boney joints
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fibrous joints
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adjacent bones are bounded by collagen fibers three kind:
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sutures
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serrate suture
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interlocking wavy lines, coronoid, sagittal, squamous, lamnoid |
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lap suture
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miter joint temporal and squamous |
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plane suture
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butt joint palatine bone |
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gomphoses
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attaches tooth to socket |
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syndesmoses
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bound by longer collagen fibers most movable (between radius and ulna) least movable (tibia to fibula) |
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Cartilaginous joints
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two bones linked by cartilage synchondroses and symphysis first ribs attached |
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synchondroses
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hyaline cartilage |
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symphysis
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fibrocartilage between the vertebrate |
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synovial joints
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bursa-synovial fluid filled sac
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between adjacent muscle and help cushion muscle |
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tendon sheath
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cylindrical covers tendon |
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ball and socket
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head in a cop hip and shoulder (only one) multiaxial |
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condylar
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one bone has a compact surface fits into a compression on the other side radial and carpals, phalanges and metacarpals bioxial joint |
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saddle joint
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both bones have depression that fit each other
bioxial |
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plane joints
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gliding joints both have a flat surface
bioxial |
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hidge joints
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one bone has a compact surface and fits into a depresion
monoxial |
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pivet joint
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radius and ulna occipital monoxial |
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zero position
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position of a joint when in standard anatomical position |
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flexion
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decreses joint angle |
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extension
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return joint to zero |
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hyperextensions
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increase joint angle beyond zero position |
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abduction
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movement away from midline of body |
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adduction
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movement towards midline of body |
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elevation
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movement that raises the body vertically |
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depression
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lowers the body vertically |
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protraction
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anterior movement of body |
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retraction
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posterior movement of body |
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circumduction
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one end stays stationary and other makes a circular motion |
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shoulder
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elbow
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hip coxal joint
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knee joint
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tibofemoral joint-----hidge joint patellorfemoral joint------gliding |
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orbicularis oculi
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o---eyelids i---eyelids |
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orbicularis oris
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o & i----lip |
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sternocleidomastoid
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flex neck o----clavicle i-----mastoid process |
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proteins that make up skeletal muscle
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contractile
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myosin and actin |
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regulatory proteins
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tropomyosin and troponin |
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accessory proteins
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dystrophin |
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thick myofilament
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myosin molecule |
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elastic myofilament
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titin- anchors thick to z disc |
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tropomyosin
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blocks active sites |
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troponin
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calcium-binding protein |
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denervation atrophy
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shrinkage of paralyzed muscle |
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somatic motor neurons
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each fiber only has one neuron but one neuron can be connected to many fibers |
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motor unit
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one nerve fiber and all the muscle fibers innervated |
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muscle fibers of one motor unit
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average motor unit
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200 muscle fibers/neuron |
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small motor units
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3-6 muscle fibert/ neuron hands and eyes |
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large motor units
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1000 muscle fibers per/neuron more strength than control calf muscles |
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neuromuscular junction
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has a synapse, and synaptic knob when target cell is a muscle |
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synapse
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where cell meets target cell |
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schwann cell
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separates nerve cell from myeline tissue |
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synaptic knob
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where it connects to target cell contains synaptic vesicles |
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neuromuscular toxins
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cholinesterase inhibitors
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tetanus
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flaccid paralysis
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curare compete with Ach for receptor sites, but do not stimulate the muscle plant poison |
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botulism
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clostridium botulinum blocks release of Ach causing flaccid paralysis botox cosmetic |
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muscle metabolism
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ATP supply depends on availability of oxygen and organic energy sources anaerobi fermentation aerobic respiration |
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anaerobic fermentation
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aerobic respiration
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ends with CO2 and water 32-36 molecules of atp |
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immediate energy need
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oxygen supplied by myoglobin phosphagen system
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short-term
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shift to anaerobic fementaion 30-40 second of max activity |
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long term
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after 40 sec. respiratory and cardiovascular system " catch up" delivers O2 fast enough for aerobic respiratory to meet ATP demands 36 ATP per glucose |
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muscle fatigue
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progressive weakness and loss of contractily
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endocrine system
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chemical messangers that are secreted in the blood |
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nervous system
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2 divisions
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CNS
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brain and spinal cord |
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PNS
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sensory division motor division |
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sensory division of PNS
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carry sensory signals to CNS Visceral ----internal organs of the body Somatic---- going to skeletal muscles |
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motor division of PNS
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issusing signals out to muscle and glands to cause reaction visceral--- sympathetic and parasympathetic somatic |
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sympathetic division of PNS
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arouse body reaction increase heart rate and increase respiration |
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Parasympathetic
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calming affect decrease heart rate and respiration |
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functional classes of nuerons
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sensory(afferent-towards cns) interneurons (confined to CNS) motor (efferent-leaving CNS) |
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soma
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control center of a neuron |
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dendrites
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recieving signals from other neurons |
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axon
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signal next cell in sequence schwann cell and synaptic knob |
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neuroglial cell of CNS
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have more than neurons (50:1) protect and assist neurons 6 types:
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astrocytes
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ependymal cell
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secrets cerebrospinal fluid |
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microglia
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wondering cells that macrophages |
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oligodendrocytes
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create the myelin sheath |
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schwann cells
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produces myelin sheath ins PNS regeneration |
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satellite cells
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electrical insulation for nerve regulate the chemical environment |
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myelination/conduction
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local potentials
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action potential
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trigger zone
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when the local potential reaches this causes the numerous of sodium gate to open causing action potential |
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threshold
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-55mV must reach in order to ope the ion gate to have the action potential |
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neurotrasmitters
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acetylcholin amino acids monoamines neuropeptides |
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amino acids
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gaba glycine aspartic acid glutamic acid |
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monoamines
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epinephrine neorepineprine dopamine serotinine histamine |
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neuropeptides
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cause foor cravings |
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excitatory postsynaptic potential
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glutamate and asparate excites the neuron making neuron more likely to fire therfore making it more positive |
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inhibitory postsynaptic potentials
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glycine and GABA any voltage change away from the threshold and make neuron less likely to follow |
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acetylcholine and norepinephrine
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act differently depending on the receptors |
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summations
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adding up all postsynaptic potentials and responding temporal and spatial |
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temporal summation
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happens when you have intense stimulation by one presynaptic neuron setting of the post synaptic neuron |
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spatial summation
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numerous presynaptic neurons simultaneously setting off the postsynaptic neuron |
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synaptic plasticity
|
ability of a synapses to change |
|
synaptic potentiation
|
process of making transmission easier along those pathways |
|
immediate memory
|
ability to hold something in your thoughts for a few minutes echos |
|
short term
|
few second to several hours can be quickly forgotten if distracted reasons: titanic stimulation and post-tenanic potentiation |
Koofers.com
|
titanic stimulation
|
rapid arrival of repetitive causes calcium to accumulate which causes the release of the neuron transmitters, causing the postsynaptic neuron to fire |
|
post-tenanic potentiation
|
ability to jog your memory cause calcium stays elevating the the synaptic knobs so little stimulation needed to jog |
|
long-term memory
|
completely change the synapses, new branching of axons and dendrites |
|
medulla oblongata
|
part of brainstem cortiocospinal tract, inferior olivary nucleus, reticular formation |
Koofers.com
|
pons
|
ascending sensory tract descending motor tracts pathways in and out of cerebellum reticular formation(sleep, respiration, and posture) |
|
midbrain
|
tectum, tegmentum and substantia nigra |
|
tectum
|
superior colliculi---visual inferior colliculi----signals from inner ear to thalamus |
|
tegmentum
|
connections go to and from cerebellum |
Koofers.com
|
substantia nigra
|
sends inhibitory signals to thalamus and basal nuclei parkinsons when this is absent |
|
thalamus
|
gateway to cerebral cortex motor control memory and emotional functions of the limbic system |
|
hypothalamus
|
mammillary nuclei pitutary gland (hormone secretion, autonomic effect, thermoregulations, food and water intake, rhythm of sleep and waking, memory, emotional behavior) |
|
cerebrum
|
frontal---voluntary function parietal----general sensory occipital----vision temporal--- hearing, smell, learning, memory, some education Insula----understanding spoken language |
Koofers.com
|
cerebullum
|
inferior peduncle---medula oblonngata middle peduncle---- pons superior peducle----- midbrain (monitors muscles, evaluation of sensory, timekeeping, hearing, planning and scheduling task) |
|
grey matter
|
neural integration cerebral cortex basal nuclei (motor control) limbic |
|
white matter
|
projection tract commisural tract association tract |
|
ventricle
|
produces cerebral spinal fluid each ventricle contains a choroid plaxu |
Koofers.com
|
cerebrospinal fluid
|
choroid plexus contains epandymal cells containing this bouyancy, protection, chemical stability |
|
brain barrier system
|
protects blood capullaries (astrocytes) |
Koofers.com
Front |
Back |
|
|---|---|---|
| Anatomy | Study of form | |
| examining the structure of the human body |
| |
| Physiology | study of function | |
| Hippocrates |
| |
| Aristotle |
| |
| Galen |
| |
| Avicenna Meimonides |
| |
| Versallus |
| |
| Hooke |
| |
| Leeuwenhook |
| |
| Schwann/Schledin |
| |
| Charles Darwin |
| |
| evolutions |
| |
| theory of natural selection |
| |
| Vestigal Organs |
| |
| Arboreal adaptations |
| |
| Bipedalism |
| |
| Atom-molecule-macromolecule-organelle-cell-tissue-organ-organsystem-organism | Hierarchy of complexity | |
| chemical elements (95% of body weight) | oxygen, carbon, hydrogen, nitrogen, calcium & phosphorous | |
| Minerals (4% body weight) | Calcium, Phosphorous, Chlorine, Mg, K, Na, I Fe, Zn, Cu & S | |
| Electrolytes | needed for nerve & muscles functions are mineral salts | |
| Radioactity | Isotopes | |
| Isotopes |
| |
| molecules | 2 or more atoms united by a chemical bond | |
| Chemical Reaction |
| |
| Decomposition Reactions |
| |
| synthesis | Small to big a + b > ab | |
| Metabolism | All the chemical reactions of the body
| |
| Catabolism | Energy releasing (exergonic) decomposition reactions | |
| Anabolism | Energy storing (endergonic) synthesis reactions
| |
| Organic Macromolecules | Carbohydrates lipids protein nucleic acid | |
| Squamous Cells | thin, flat , and often have a bulge where the nucleus is much like the shape of a fried egg | |
| Polygonal cells | irregularly angular shaped with four, five, or more sides | |
| Stellate cell | nerve cells that have multiple extensions that give them a starlike shape | |
| Cuboidal Cells | squarish and approximately as tall as they are wide | |
| Columnar Cells | line the intestines and are markedly taller than wide liver cells are good example | |
| Spheroid | egg cells and fat cells round to ovale | |
| Fibrous | Skeletal muscle cells
| |
| 10 - 15 micrometers in diameter | human cell size | |
| 100 micrometer in diameter | egg cells | |
| 1 meter long | nerve cells | |
| Major constituents of cell |
| |
| Plasma Membrane | made of proteins and lipids | |
| Cytosol | intercellular fluid | |
| Diffusion |
| |
| temp, molecular weight, steepness of gradient, membrane surface area, membrane permeability | factors that affect the diffusion rate | |
| Temperature | increase temp increase the motion | |
| molecular weight | larger molecules move slower | |
| steepness of gradient | increase the difference and increase the rate | |
| membrane surface area | increase the area increase the rate | |
| membrane permeability | increase the permeability and increase the rate | |
| osmosis | flow of water from side w/ higher water concentration to the side with lower water concentration across a selectively permeable membrane | |
| hypotonic environment | environment has less concentration of solute cell swells and may burst (lyse) | |
| hypertonic environment | environment has more concentration of solute cell may shrink and shrivel (crenate) | |
| Isotonic solution | everything equals inside and outside environments no change in shape nor size | |
| Active transport | carrier-mediated trasport of solute through a membrane up (against) its concentration gradient ATP energy is consumed examples: sodium potassium pump keeps K+ concentration higher inside the cell | |
| sodium potassium pump (ICF, ECF) | consumes one ATP and exchanges three Na+ for 2 K+ K+ is higher in Na+ is higher in | |
| Vescular Transport | processes that move particles through the membrane in vesicles | |
| Endocytosis | vesicular processes that bring material into the cell phagoyctosis pinocytosis receptor | |
| Phagoctosis | cell eating (white blood cells) | |
| Pinocytosis | cell drinking | |
| Receptor | mediated endocytosis----particle bind to specific receptor on plasma membrane | |
| Exocytosis | discharging material from the cell example: discharge of insulin | |
| receptor mediated endocytosis |
| |
| Neutrophil Phagocytosis | 5 different types white blood cells | |
| Integuma system | protection skin, hair, naile | |
| Skeletal System | structure, support | |
| muscular system | movement | |
| lymphatic system | lymph nodes, tonsils, speed, thymus lympthatic organs are dominated by WBCs | |
| Respiratory System | Cellular respiration | |
| urinary system | removing wastes/ regulates blood pressure | |
| nervous system | sensory & internal communication | |
| endocrine system | hormones | |
| circulatory system | blood flow, distribution of nutrients heart and blood vessels blue blood until it reaches the lungs ; further from heart darker blood | |
| Digestive system | nutrients breakdown and absorption metabolism and disposal and cleansing of blood | |
| reproductive system | dont need this to live | |
| anatomical position | standard frame of reference for anatomical descriptions & dissections palms are supinated (face foward) | |
| Sagittal Plane | right and left regions median (midsagittal) plane | |
| Frontal Plane | anterior (front) and Posterior (back) portions | |
| transverse Plane | superior (upper) and inferior (lower) portions | |
| ventral/ dorsal | going toward front/back | |
| superior/inferior | above/below | |
| proximal/distal | close to pt attachment/ far | |
| medial/lateral | toward inside/ outside | |
| superficial/deep | close to surface/ far | |
| homeostasis | body's ability to detect change and activate mechanisms that oppose it. | |
| negative feedback | keeps variable close to the set point example thermoregulation | |
| positive feedback | leads to greater change in the same directions example: child birth | |
| Epithelium Tissue |
| |
| simple epithelia | all cells touch basement membrane can be: simple squamous simple cuboidal simple columnar pseudostratified | |
| stratified epithelia | not all cell touch basement membrane; multiple layers 2 to 20 or more layers of cells can be: stratified squamous stratified cuboidal stratified columnar transitional epithelium | |
| simple squamous |
| |
| simple cuboidal |
| |
| simple columnar |
| |
| Psudostratified |
| |
| goblet cells | mucus secreting cells | |
| stratified squamous | keratinized and non karatinized | |
| keratinized |
| |
| nonkeratinized |
| |
| stratified cuboidal |
| |
| transitional epithelium | change from round to flat when stretched example: ureter and bladder | |
| connective tissue |
four types: fibrous, loose, dense, supportive | |
| fibrous CT | cells (fibroblast, macrophages, leukocytes, plasma cells, mast cells, adipocytes) fibers (collagenous, reticular, elastic) | |
| Macrophages | fibrous cells able to phagocytise | |
| Leukocytes | fibrous white blood cells immune protection | |
| Plasma Cells | fibrous CT cell that secretes antibodies | |
| Mast Cell | fibrous CT cell secret heparin and histamine | |
| heparin | blood doesnt clot | |
| histamine | widen blood vessels | |
| adipocytes | fibrous ct fat cells store lipids | |
| collagenous fibers | cant stretch | |
| reticular fibers | coated with glycoprotein | |
| elastic fibers | very stretchable | |
| Loose CT | Areolar tissue reticular tissue adipose tissue | |
| areolar tissue | all cell types present, mostly collagenus fibers underlies all epithelia, in serous membrane, between muscles, passageways for nerves and blood vessels | |
| reticular tissue | mesh of reticular fibers and fibroblasts found in lymph nodes, spleen, thymus, and bone marrow | |
| adipose tissue | energy storage, insulation, cushioning areolar tissue, reticular tissue, and blood capillaries between cells | |
| Dense CT | Dense regular and Dense irregular | |
| Dense regular | all fibers running parallel tendons and ligaments | |
| tendons | muscle to bone most important to stabilizing joing | |
| ligaments | bone to bone | |
| dense irregular | deeper layer of skin; capsules around organs | |
| supportive CT | cartilage
| |
| hyaline cartilage |
| |
| elastic cartilage |
| |
| Fibrocartilage |
| |
| fluid CT | blood | |
| blood | plasma forms : erythrocytes, leukocyte, and platelets | |
| erythrocytes |
| |
| leukocytes |
| |
| Platelets |
| |
| muscular and nervous | excitable tissues | |
| nervous tissue |
| |
| neurosoma | cell body | |
| dendrites |
| |
| axon | nerve fiber
| |
| muscular tissue |
three types
| |
| skeletal muscle |
| |
| cardiac muscle |
| |
| smooth muscles |
example: labor | |
| endocrine Glands | lose contact with surface
| |
| exocrine glands | maintain contact with body surface by way of a duct type:
| |
| serous glands | produce thin, watery secretions type of exocrine gland | |
| mucous glands | found on tongue and roof of mouth type of exocrine glands | |
| mixed glands | both serous and mucous glands | |
| cytogenic glands | release whole cells sperm and egg cells | |
| methods of secretion | merocrine glands apocrine glands holocrine glands | |
| merocrine glands | vesicles release secretion by exocytosis
| |
| apocrine glands | merocrine mode of secretion
| |
| holocrine gland | cells accumulate a product and the entire cell disintegrates
| |
| epidermis | karatinized stratified squamous 5 layers: stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, stratum basale
| |
| stratum corneum |
| |
| stratum lucidum |
| |
| stratum granulosum | 3-5 layers thick keratohyalin granule
| |
| stratum spinosum | thickest in most skin produces keratin filaments 8-10 cells thick | |
| stratum basale | one cell layer thick stem cells divide keratinocytes melanocytes----melanin tactile (merkel) cells----touch receptor cells | |
| dermis |
| |
| malignant melanoma |
| |
| basal cell carcinoma | most common arises from cells in stratum basal | |
| squamous cell carcinoma |
| |
| papillary layer |
| |
| reticular layer |
| |
| hypodermis |
| |
| cyanosis | deficiency of oxygen in blood cold weather, airway abstruction | |
| erythema | dilated cutaneous vessels hot weather, exercise, anger | |
| pallor | little blood flow through the skin low blood pressure, anemic, circulatory shock | |
| albinism | genetic lack of melanin | |
| jaundice | excess of bilirubin in blood yellowing of skin, eye | |
| hematoma | mass of clotted blood bruise, hicky | |
| flat | curly hair shape | |
| round | straight hair shape | |
| red hair | more phamelanin than eumalanin | |
| black hair | high concentration of eumalanin | |
| blonde hair | very little eumalanin more phamelanin | |
| grey | absence of melanin cortex become hollowed out | |
| debridement | removal of eschar | |
| 1st degree burn | havent gone through the skin | |
| 2nd degree burn | gone throught the dermis | |
| 3rd degree burn | need skin graphs burn through the dermis and epidermis down to bone | |
| functions of the skin |
| |
| resistance to trauma and infection | keratin acid mantle | |
| other barrier functions | waterproofing UV radiation harmful chemicals | |
| Vitamin D synthesis | skin first step liver and kidneys complete process | |
| sensation | skin is our most extensive sense organ | |
| thermoregulation | thermoreceptors vasoconstriction/ vasodilation | |
| nonverbal communication | acne, birthmark, or scar | |
| Transdermal absorption | administration of certain drugs steadily through this skin----adhesive patches | |
| Long, short, flat, irregular | ||
| Long bone | rigid levers acted upon by muscle (femur and ulna) structure:
| |
| periosteum | outer layer of long bone | |
| endosteum | inner layer of long bone cells that can deposit or breakdown | |
| nutrient foramina | blood vessels are allowed to penetrate the bones | |
| epiphyses | large end of long bone | |
| diaphysis | shaft of long bone | |
| epiphysial line | seperates piphyses from diaphysis in adults | |
| compact | surface of all bones | |
| spongy | in the ends of long bones | |
| marrow cavity | in the middle and contains the marrow | |
| short bones | glide across one another in multiple directions carpals and tarsals | |
| flat bones | protect soft organs scapula, sternum, cranial, ribs | |
| irregular bones | skull bones vertebrate, sphenoid, ethnoid | |
| bone marrow | red----- myeloid tissue (child) yellow----(adults) | |
| four principle types of bone cells | osteogenic cell osteoblasts osteocytes osteoclast | |
| osteogenic cell | give rise to osteoblast stem cell | |
| osteoblast | buil start producing matrix to form bone becomes trapped in matrix and becomes osteocytes | |
| osteocytes | mature bone cell | |
| osteoclast | catastrophe same stem cell as blood develops from stem cells from a different origin surface of bone bone dissolving cells | |
| compact bone |
| |
| spongy bone |
| |
| osteogenesis | in the human fetus and infant, bone develops by two methods: intramembranous ossification endochondral ossification | |
| interstitial growth | part of bone growth bones increase in length | |
| appositional growth | the deposition of new bone at the surface | |
| bone remodeling | occurs throughout life 10% per year | |
| Achondroplastic dwarfism | failure of cartilage growth in metaphysis | |
| pituitary dwarfism | lack of growth hormone | |
| calcium homeostasis | is regulated by three hormones: calcitriol, calcitonin, and parathyroid hormone | |
| hypocalcemia | blood calcium deficiency Na enters cells to easily and excites muscle spasms, tenisis | |
| hypercalcemia | blood calcium excess Na channels less responsive, nerve and muscular tissue depress and slugish very rare | |
| calcitriol |
| |
| calcitonin | decreases blood calcium back to normal produced by the thyroid gland | |
| parathyroid hormone secretion | correction for hypocalcemia
| |
| stress fracture | abnormal trauma to a bone | |
| pathological fracture | weakend by disease | |
| nondisplaced | cracked but bones still aligned | |
| displaced | bones are not aligned completely broken | |
| comminuted | bones broken in 3 or more places | |
| greenstick | incomplete fractured causing stress on another bone | |
| closed treatment | no surgery | |
| opened treatment | plates screws to fix | |
| boney joints |
| |
| fibrous joints | adjacent bones are bounded by collagen fibers three kind:
| |
| sutures |
| |
| serrate suture | interlocking wavy lines, coronoid, sagittal, squamous, lamnoid | |
| lap suture | miter joint temporal and squamous | |
| plane suture | butt joint palatine bone | |
| gomphoses | attaches tooth to socket | |
| syndesmoses | bound by longer collagen fibers most movable (between radius and ulna) least movable (tibia to fibula) | |
| Cartilaginous joints | two bones linked by cartilage synchondroses and symphysis first ribs attached | |
| synchondroses | hyaline cartilage | |
| symphysis | fibrocartilage between the vertebrate | |
| synovial joints |
| |
| bursa-synovial fluid filled sac | between adjacent muscle and help cushion muscle | |
| tendon sheath | cylindrical covers tendon | |
| ball and socket | head in a cop hip and shoulder (only one) multiaxial | |
| condylar | one bone has a compact surface fits into a compression on the other side radial and carpals, phalanges and metacarpals bioxial joint | |
| saddle joint | both bones have depression that fit each other
bioxial | |
| plane joints | gliding joints both have a flat surface
bioxial | |
| hidge joints | one bone has a compact surface and fits into a depresion
monoxial | |
| pivet joint | radius and ulna occipital monoxial | |
| zero position | position of a joint when in standard anatomical position | |
| flexion | decreses joint angle | |
| extension | return joint to zero | |
| hyperextensions | increase joint angle beyond zero position | |
| abduction | movement away from midline of body | |
| adduction | movement towards midline of body | |
| elevation | movement that raises the body vertically | |
| depression | lowers the body vertically | |
| protraction | anterior movement of body | |
| retraction | posterior movement of body | |
| circumduction | one end stays stationary and other makes a circular motion | |
| shoulder |
| |
| elbow |
| |
| hip coxal joint |
| |
| knee joint | tibofemoral joint-----hidge joint patellorfemoral joint------gliding | |
| orbicularis oculi | o---eyelids i---eyelids | |
| orbicularis oris | o & i----lip | |
| sternocleidomastoid | flex neck o----clavicle i-----mastoid process | |
| proteins that make up skeletal muscle |
| |
| contractile | myosin and actin | |
| regulatory proteins | tropomyosin and troponin | |
| accessory proteins | dystrophin | |
| thick myofilament | myosin molecule | |
| elastic myofilament | titin- anchors thick to z disc | |
| tropomyosin | blocks active sites | |
| troponin | calcium-binding protein | |
| denervation atrophy | shrinkage of paralyzed muscle | |
| somatic motor neurons | each fiber only has one neuron but one neuron can be connected to many fibers | |
| motor unit | one nerve fiber and all the muscle fibers innervated | |
| muscle fibers of one motor unit |
| |
| average motor unit | 200 muscle fibers/neuron | |
| small motor units | 3-6 muscle fibert/ neuron hands and eyes | |
| large motor units | 1000 muscle fibers per/neuron more strength than control calf muscles | |
| neuromuscular junction | has a synapse, and synaptic knob when target cell is a muscle | |
| synapse | where cell meets target cell | |
| schwann cell | separates nerve cell from myeline tissue | |
| synaptic knob | where it connects to target cell contains synaptic vesicles | |
| neuromuscular toxins |
| |
| cholinesterase inhibitors |
| |
| tetanus |
| |
| flaccid paralysis | curare compete with Ach for receptor sites, but do not stimulate the muscle plant poison | |
| botulism | clostridium botulinum blocks release of Ach causing flaccid paralysis botox cosmetic | |
| muscle metabolism | ATP supply depends on availability of oxygen and organic energy sources anaerobi fermentation aerobic respiration | |
| anaerobic fermentation |
| |
| aerobic respiration | ends with CO2 and water 32-36 molecules of atp | |
| immediate energy need | oxygen supplied by myoglobin phosphagen system
| |
| short-term | shift to anaerobic fementaion 30-40 second of max activity | |
| long term | after 40 sec. respiratory and cardiovascular system " catch up" delivers O2 fast enough for aerobic respiratory to meet ATP demands 36 ATP per glucose | |
| muscle fatigue | progressive weakness and loss of contractily
| |
| endocrine system | chemical messangers that are secreted in the blood | |
| nervous system |
2 divisions
| |
| CNS | brain and spinal cord | |
| PNS | sensory division motor division | |
| sensory division of PNS | carry sensory signals to CNS Visceral ----internal organs of the body Somatic---- going to skeletal muscles | |
| motor division of PNS | issusing signals out to muscle and glands to cause reaction visceral--- sympathetic and parasympathetic somatic | |
| sympathetic division of PNS | arouse body reaction increase heart rate and increase respiration | |
| Parasympathetic | calming affect decrease heart rate and respiration | |
| functional classes of nuerons | sensory(afferent-towards cns) interneurons (confined to CNS) motor (efferent-leaving CNS) | |
| soma | control center of a neuron | |
| dendrites | recieving signals from other neurons | |
| axon | signal next cell in sequence schwann cell and synaptic knob | |
| neuroglial cell of CNS | have more than neurons (50:1) protect and assist neurons 6 types:
| |
| astrocytes |
| |
| ependymal cell | secrets cerebrospinal fluid | |
| microglia | wondering cells that macrophages | |
| oligodendrocytes | create the myelin sheath | |
| schwann cells | produces myelin sheath ins PNS regeneration | |
| satellite cells | electrical insulation for nerve regulate the chemical environment | |
| myelination/conduction |
| |
| local potentials |
| |
| action potential |
| |
| trigger zone | when the local potential reaches this causes the numerous of sodium gate to open causing action potential | |
| threshold | -55mV must reach in order to ope the ion gate to have the action potential | |
| neurotrasmitters | acetylcholin amino acids monoamines neuropeptides | |
| amino acids | gaba glycine aspartic acid glutamic acid | |
| monoamines | epinephrine neorepineprine dopamine serotinine histamine | |
| neuropeptides | cause foor cravings | |
| excitatory postsynaptic potential | glutamate and asparate excites the neuron making neuron more likely to fire therfore making it more positive | |
| inhibitory postsynaptic potentials | glycine and GABA any voltage change away from the threshold and make neuron less likely to follow | |
| acetylcholine and norepinephrine | act differently depending on the receptors | |
| summations | adding up all postsynaptic potentials and responding temporal and spatial | |
| temporal summation | happens when you have intense stimulation by one presynaptic neuron setting of the post synaptic neuron | |
| spatial summation | numerous presynaptic neurons simultaneously setting off the postsynaptic neuron | |
| synaptic plasticity | ability of a synapses to change | |
| synaptic potentiation | process of making transmission easier along those pathways | |
| immediate memory | ability to hold something in your thoughts for a few minutes echos | |
| short term | few second to several hours can be quickly forgotten if distracted reasons: titanic stimulation and post-tenanic potentiation | |
| titanic stimulation | rapid arrival of repetitive causes calcium to accumulate which causes the release of the neuron transmitters, causing the postsynaptic neuron to fire | |
| post-tenanic potentiation | ability to jog your memory cause calcium stays elevating the the synaptic knobs so little stimulation needed to jog | |
| long-term memory | completely change the synapses, new branching of axons and dendrites | |
| medulla oblongata | part of brainstem cortiocospinal tract, inferior olivary nucleus, reticular formation | |
| pons | ascending sensory tract descending motor tracts pathways in and out of cerebellum reticular formation(sleep, respiration, and posture) | |
| midbrain | tectum, tegmentum and substantia nigra | |
| tectum | superior colliculi---visual inferior colliculi----signals from inner ear to thalamus | |
| tegmentum | connections go to and from cerebellum | |
| substantia nigra | sends inhibitory signals to thalamus and basal nuclei parkinsons when this is absent | |
| thalamus | gateway to cerebral cortex motor control memory and emotional functions of the limbic system | |
| hypothalamus | mammillary nuclei pitutary gland (hormone secretion, autonomic effect, thermoregulations, food and water intake, rhythm of sleep and waking, memory, emotional behavior) | |
| cerebrum | frontal---voluntary function parietal----general sensory occipital----vision temporal--- hearing, smell, learning, memory, some education Insula----understanding spoken language | |
| cerebullum | inferior peduncle---medula oblonngata middle peduncle---- pons superior peducle----- midbrain (monitors muscles, evaluation of sensory, timekeeping, hearing, planning and scheduling task) | |
| grey matter | neural integration cerebral cortex basal nuclei (motor control) limbic | |
| white matter | projection tract commisural tract association tract | |
| ventricle | produces cerebral spinal fluid each ventricle contains a choroid plaxu | |
| cerebrospinal fluid | choroid plexus contains epandymal cells containing this bouyancy, protection, chemical stability | |
| brain barrier system | protects blood capullaries (astrocytes) |
© Copyright 2012 , Koofers, Inc. All rights reserved.
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