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Past Exam for BIMM 118 - Pharmacology at UC San Diego (UCSD)

Exam Information

Material Type:Mid-Term
Professor:Staff
Class:BIMM 118 - Pharmacology
Subject:Biology/Molec Biol, Microbiol
University:University of California - San Diego
Term:Winter 2008
Keywords:
  • Tachycardia
  • Antagonists
  • Erythromycin
  • Mao Inhibitors
  • Catecholamines
  • Scopolamine
  • Side Effect
  • Consequence
  • Surveillance
  • Acetylcholine
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Sample Document Text

BIMM118 – Midterm ’08 NOTE: WRONG answers on multiple choice questions will result in the DEDUCTION of the points !!!!! 1) A drug that is a partial agonist a) binds to the same site on the receptor as the natural ligand b) binds the receptor irreversibly c) does not elicit a response from the receptor d) shifts the dose-response curve of the natural ligand to the right e) shifts the dose-response curve of the natural ligand to the right AND down (5 pts each) 2) What are the Vd and t1/2? How are they interconnected (explain the underlying concept!)? Vd = volume of distribution; t1/2= half-life. Typically, drugs with a large Vd are highly protein bound, and their metabolism/excretion is therefore attenuated. Consequently, drugs with a large Vd have usually a longer half-life than drugs with small Vd. (10 pts) 3) According to the diagram a) Both drugs have the same efficacy b) Drug B has higher efficacy c) The drugs have different potency d) Drug B has the lower potency e) Drug A is...

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