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Lecture Notes for BIOL 3124 - Cell Physiology at Virginia Tech (VT)

Notes Information

Material Type:Review Sheet 1
Professor:Staff
Class:BIOL 3124 - Cell Physiology
Subject:Biological Sciences
University:Virginia Polytechnic Institute And State University
Term:Fall 2008
Keywords:
  • Human Heart
  • Either...or
  • Microtubule
  • Concentration
  • Participating
  • Hydrophobic
  • Association
  • Cytoskeleton
  • Differences
  • Behind (of)
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Page 1 BIOL 3124, Problem Set 3 Membranes and Cytoskeleton 1. Synthesis of Gastric Juice. Gastric juice (pH 1.5) is produced by pumping HCl from blood plasma (pH 7.4) into the stomach. (a) Calculate the amount of free energy per mole of H + pumped into the stomach to form gastric juice at 37 ēC. Ignore the effects of the transmembrane electrical potential. (b) Under cellular conditions, how many moles of ATP must be hydrolyzed to provide this amount of free energy? The free-energy change for ATP hydrolysis under cellular conditions is about -58 kJ/mol. (a) First, calculate the concentrations of protons in each compartment, then the ?G for the gradient. pH = -log[H + ] ? [H + ] = 10 -pH . [H + plasma ] = 10 -7.4 = 4.0×10 -8 M [H + stomach ] = 10 -1.5 = 0.032 M ?G = RT ln ][H ][H plasma stomach + + = (8.315 Kmol J ? )(310ēK) ln 8 104 032.0 ? × = 35 kJ/mol. (Neglecting the effects of the transmembrane electrical potential) (b) Since ATP h...

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