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NPBlec26 - Flashcards

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Class:NPB 101 - Systemic Physiology
Subject:Neurobiology,Physio & Behavior
University:University of California - Davis
Term:Fall 2010
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The PNS fires at basal rate which ____ rate slightly slows.
increase PNS stimulation, _______ heart rate decrease (because AP takes longer to reach threshold)
increase SNS stimulation, _______ heart rate increase, and it can GREATLY increase (unlike PNS which only slightly affects rate, in other words, PNS cannot significantly decrease heart rate but SNS can greatly increase it)
PNS is mainly _______ innervation arterial
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PNS _______ cardiac contractile force in atrial myocardial tissue decreases. (note: myocardial= muscle tissue of heart)
SNS densely innervates both atrial and ventral myocardial tissue, therefore it ... has more control over contractile function
SNS can have a weak or profound ______ in force (in both atria and ventricles) increase
diastole period of filling ventricles
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systole period of emptying ventricles
at rest, cardiac muscle operates below optimum of ventricle (2.2-2.5, like skeletal) because... when stimulated it still develops a force, although not nearly as much as physically possible. this dictated by other means of control (extrinsic: hormones, innervation SNS, etc)
operating below optimum fiber length is an example of an ______ regulatory mechanism intrinsic
what happens when ventricles overfill? contractile proteins can't adequately interact. this is the cause of congestive heart failure: ventricle weakened by age or pathology, lacks ability to fully empty (systole) so stretches even more during filling (diastole), eventually won't be able to have enough force to eject blood during systole
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Frank-Starling Law of Heart ventricles: cardiac output matches left and right sides. filling of left ventricle determines filling of right. in other words, within physiological limits, the heart has the ability to pump out all of the blood that gets returned to it. OR CARDIAC OUTPUT = VENUS RETURN
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 The PNS fires at basal rate which ____ rate slightly slows.
 increase PNS stimulation, _______ heart ratedecrease (because AP takes longer to reach threshold)
 increase SNS stimulation, _______ heart rateincrease, and it can GREATLY increase (unlike PNS which only slightly affects rate, in other words, PNS cannot significantly decrease heart rate but SNS can greatly increase it)
 PNS is mainly _______ innervationarterial
 PNS _______ cardiac contractile force in atrial myocardial tissuedecreases. (note: myocardial= muscle tissue of heart)
 SNS densely innervates both atrial and ventral myocardial tissue, therefore it ...has more control over contractile function
 SNS can have a weak or profound ______ in force (in both atria and ventricles)increase
 diastole period of filling ventricles
 systoleperiod of emptying ventricles
 at rest, cardiac muscle operates below optimum of ventricle (2.2-2.5, like skeletal) because...when stimulated it still develops a force, although not nearly as much as physically possible. this dictated by other means of control (extrinsic: hormones, innervation SNS, etc)
 operating below optimum fiber length is an example of an ______ regulatory mechanismintrinsic
 what happens when ventricles overfill?contractile proteins can't adequately interact. this is the cause of congestive heart failure: ventricle weakened by age or pathology, lacks ability to fully empty (systole) so stretches even more during filling (diastole), eventually won't be able to have enough force to eject blood during systole
 Frank-Starling Law of Heartventricles: cardiac output matches left and right sides. filling of left ventricle determines filling of right. in other words, within physiological limits, the heart has the ability to pump out all of the blood that gets returned to it. OR CARDIAC OUTPUT = VENUS RETURN
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